CRISPR Gene Design API

Design CRISPR GUID RNAs for any DNA sequence. SpCas9, SaCas9, Cas12a supported. Off-target analysis included. On-premise -- sequences never stored.

1 subscribers
5 endpoints
The in-depth APIMemo review for this API hasn't been published yet — the data below comes straight from the public marketplace listing.

CRISPR Gene Design API endpoints

MethodEndpointDescription
CRISPR Design
POST crispr_score
/crispr/score
Score an existing guide RNA sequence for predicted on-target cleavage efficiency. Uses rule-based scoring incorporating GC content, seed region composition, and PAM proximal…
POST crispr_batch
/crispr/batch
Design guide RNAs for multiple sequences in a single call. Process up to 100 sequences simultaneously. Results returned as an array in the same order as input sequences.…
POST crispr_design
/crispr/design
Design ranked guide RNAs for a target DNA sequence. Returns scored guide RNAs with GC content, PAM sites, and strand information. Guides are ranked by predicted on-target…
Off-Target Analysis
POST crispr_offtarget
/crispr/offtarget
Scan a genome region for potential off-target cleavage sites for a given guide RNA. Returns ranked off-target sites with mismatch counts and predicted cleavage scores. Lower…
Reference
GET crispr_nucleases
/crispr/nucleases
Returns all supported CRISPR nucleases with their PAM sequences, cut patterns, and recommended use cases. **Free endpoint** — no quota consumed.

CRISPR Gene Design API pricing

PlanPriceRate limitQuotas
BASIC Free
  • Requests: 10 / monthly
  • List Nucleases: 0 / monthly
PRO $19.99 / month
  • Requests: 500 / monthly
  • List Nucleases: 0 / monthly (then $0.0250 each)
  • Design Guide RNAs: 0 / monthly (then $0.0250 each)
  • Score a Guide RNA: 0 / monthly (then $0.0250 each)
ULTRA $49.99 / month 10 / second
  • Requests: 2,000 / monthly
  • List Nucleases: 0 / monthly (then $0.0150 each)
  • Batch Design.: 0 / monthly (then $0.0150 each)
  • Design Guide RNAs: 0 / monthly (then $0.0150 each)
  • Score a Guide RNA: 0 / monthly (then $0.0150 each)
MEGA $199.99 / month 30 / second
  • Requests: 10,000 / monthly
  • List Nucleases: 0 / monthly (then $0.0080 each)
  • Batch Design.: 0 / monthly (then $0.0080 each)
  • Design Guide RNAs: 0 / monthly (then $0.0080 each)
  • Score a Guide RNA: 0 / monthly (then $0.0080 each)
  • Off=Target Analysis: 0 / monthly (then $0.0080 each)

More Science APIs

View all →
  • High Precision Astrology API – Powered by Kerykeion, the Leading Library for Precise Birth, Synastry Charts,…

    ScienceFreemium3k subscribers
  • 20,000+ Users - The MoonAPI provides lunar and astronomical data, including moon phases, sun data, eclipses…

    ScienceFreemium408 subscribers
  • Carbon Emission Footprint Estimation for Organizations.

    ScienceFreemium662 subscribers
  • Quickly retrieve original Arabic text, translation, transliteration and Word Search from the Koran /Quran

    ScienceFree1.9k subscribers
  • Get statistics on thousands of planets in the known universe. Unlock all data and parameters at…

    ScienceFreemium1.5k subscribers
  • This API provides on a quasi-daily basis, the amount of carbon dioxide (CO2) in the atmosphere from…

    ScienceFree821 subscribers